Description

Xapavir 50 (Dolutegravir 50 mg) is a powerful integrase inhibitor used in antiretroviral therapy (ART) for HIV-1 infection. It works to block HIV from integrating its genetic material into human cells, thereby reducing viral replication.

Key Features:

Highly potent integrase strand transfer inhibitor (INSTI)

Once-daily dosing with or without food for improved adherence

Supports long-term viral suppression

Minimal drug interactions compared to older ART regimens

Composition:

Active Ingredient: Dolutegravir 50 mg

Excipients: Inert substances ensuring tablet stability and bioavailability

Usage Instructions

Consultation: Use only under HIV specialist supervision.

Dosage: Take one 50 mg tablet once daily, as prescribed.

Administration: Swallow with water, can be taken with or without food.

Missed Dose: Take as soon as remembered; do not double dose.

Adherence: Maintain strict adherence for optimal viral suppression.

Medicinal Advantages

Reduces HIV viral load effectively, helping restore immune function

Prevents disease progression to AIDS

Improves CD4+ cell count, supporting immunity

Once-daily regimen enhances patient compliance

Evidence: Clinical trials demonstrate Dolutegravir’s high efficacy, low resistance potential, and favorable safety profile, making it a WHO-recommended first-line therapy.

Side Effects

Common (mild):

Headache

Insomnia

Nausea

Fatigue

Serious (rare):

Hypersensitivity reactions (rash, fever, swelling)

Liver dysfunction in pre-existing liver disease

Note: Always consult a healthcare professional before starting or adjusting therapy.