Description

Acestine 600 is formulated with N-Acetylcysteine (NAC), a derivative of the amino acid L-cysteine. It works as:

A mucolytic agent – breaks down disulfide bonds in mucus, reducing thickness.

An antioxidant precursor – replenishes glutathione levels, a key antioxidant in the body.

It is commonly prescribed for:

Chronic bronchitis

COPD (Chronic Obstructive Pulmonary Disease)

Sinusitis with thick mucus

Productive cough

In hospital settings, NAC is also used in specific protocols for acetaminophen (paracetamol) overdose management (different dosing).

 

Usage Instructions

⚠️ Follow your doctor’s prescription carefully.

Take one 600 mg tablet once or twice daily as advised.

Swallow with water after meals.

Do not crush unless instructed.

Maintain adequate hydration for best mucus-clearing effect.

Complete full treatment duration if prescribed.

Dosage may vary depending on condition and severity.

 

Medicinal Advantages

When used appropriately, Acestine 600 may provide:

Thinner mucus for easier expectoration

Improved airway clearance

Reduced cough severity

Enhanced lung comfort

Antioxidant support for respiratory tissues

Clinical studies show NAC helps reduce exacerbations in chronic bronchitis patients when used long-term under supervision.

 

Mechanism of Action

N-Acetylcysteine works through two primary mechanisms:

1️⃣ Mucolytic Action

It breaks disulfide bonds in mucus glycoproteins, reducing viscosity and making secretions easier to expel.

2️⃣ Antioxidant Action

It replenishes intracellular glutathione levels, protecting lung cells from oxidative stress and inflammation.

 

Side Effects

Common side effects:

Nausea

Vomiting

Stomach discomfort

Mild rash

Rare but serious:

Severe allergic reaction

Bronchospasm in sensitive individuals

Consult your doctor immediately if severe symptoms occur.